NG12

Prevention Of Radiation-induced Dermatitis

Status: Formulation Optimisation Underway

Radiation-induced dermatitits is a very common complication of radiotherapy: 95% of treated patients experience dermatitis on radiation-exposed skin.

Symptoms commence within a few days or weeks after the start of radiotherapy, and range from redness (Grade 1) and swelling (Grade 2-3) to blisters and ulceration (Grade 3-4).

In severe cases, radiotherapy needs to be discontinued.

The head & neck region, breast, chest wall and genital areas are particularly prone to dermatitis.

Our preliminary human data for NG12 demonstrates a substantial reduction in skin erythema following radiotherapy